Early exposure to alcohol, especially during critical periods such as pregnancy or adolescence, can lead to alcohol abuse and harmful consequences. Numerous surveys estimate that a large percentage of women consume alcohol during the first trimester of pregnancy, and a large number of adolescents consume alcohol excessively. These consumption patterns can alter oxidative stress metabolism and cause patterns of anxiety and depression. These effects have been studied in animal models, and one way to mitigate them is through dietary supplements such as folic acid and selenium, which can help restore the metabolism. In our research, we want to expand our knowledge of treatments with enriched diets and early exposure to alcohol. Specifically, we will study the offspring of mothers exposed to alcohol during gestational days 7-9. We expect their offspring to consume more alcohol, have an anxious and depressive phenotype, and have memory problems. We will also analyze the antioxidant capacity of the supplemented diet and observe whether there are differences between the groups, expecting an improvement in the supplemented group. The data obtained show that early alcohol consumption by the mother leads to high consumption in adolescence. Likewise, antioxidant enzymes such as PON1 show lower activity in adolescents with high alcohol consumption. Translated with DeepL.com (free version)