Alcohol hangover is a transient pathophysiological state that begins when blood alcohol concentration (BAC) approaches zero and is characterized by physical and cognitive impairments that may last for several hours. While the acute effects of alcohol intoxication on cognitive performance are well documented, the specific impact of hangover on memory processes remains less understood. Within the framework of an undergraduate thesis, this study aimed to explore the effects of alcohol hangover on inhibitory avoidance memory in female CF-1 mice. Animals received intraperitoneal injections of veh (control), 1.9 g/kg, or 3.8 g/kg ethanol. Training was conducted at 6, 9, or 12 hours post-administration, representing different stages of the hangover period, and memory retention was evaluated 48 hours later using the inhibitory avoidance task. Preliminary findings suggest that hangover impairs memory retention in a dose- and time-dependent manner. The most significant deficits were observed in mice treated with 3.8 g/kg ethanol and trained at earlier hangover stages, indicating that both the intensity of exposure and the timing of learning relative to hangover onset critically influence cognitive outcomes. These results provide initial evidence that alcohol hangover interferes with memory consolidation mechanisms, underscoring its potential impact on cognitive performance beyond acute intoxication.